নির্দেশনা

Trimebutine Maleate is indicated for- Treatment and relief of symptoms associated with Irritable Bowel Syndrome (IBS). Postoperative paralytic ileus in order to accelerate the resumption of the intestinal transit following abdominal surgery.

Composition

ফার্মাকোলজি

Trimebutine Maleate is a noncompetitive spasmolytic agent.lt possesses moderate opiate receptor affinity and has marked anti-serotonin activity especially on 'mu' receptors. It induces regulation of spontaneous activity and increases synchronization between electrophysiological spikes and contractions in isolated guinea pig strips of colon and ileum. However, it does not alter normal motility, but regulates abnormal intestinal activity.

মাত্রা ও সেবনবিধি

Children over 12 years and Adults: 1 or 2 tablets, 3 times/day before meals.

প্রতিনির্দেশনা

Patients with known hypersensitivity to Trimebutine Maleate or any excipient.

পার্শ্ব প্রতিক্রিয়া

Trimebutine Maleate is generally well tolerated. The infrequently reported adverse effects are as follows: dry mouth, foul taste, diarrhea, dyspepsia, epigastric pain, nausea, constipation, drowsiness, fatigue, dizziness, hot/cold sensations, headache etc.

গর্ভাবস্থায় ও স্তন্যদানকালে

Although teratological studies have not shown any drug related adverse effects on the course and outcome of pregnancy, the use of Trimebutine Maleate in pregnant women is not recommended. It is not known ifTrimebutine Maleate passes into breast milk. This medication should be used while breast feeding only if the potential benefits outweigh risks to the nursing infants.

সতর্কতা

Elderly, pregnancy and lactation

থেরাপিউটিক ক্লাস

Anticholinergics

সংরক্ষণ