Indications

Monosulfiram solution is a parasiticide, active against the burrowing mite Sarcoptes scabiei. It is indicated for the treatment and prophylaxis of scabies.

Composition

Pharmacology

Monosulfiram, is an ectoparasiticide used in the treatment and prevention of scabies.

Dosage & Administration

Before application Monosulfiram Solution should be diluted with two to three parts of water. The patient's body should be liberally washed with soap and water and thoroughly dried. Apart from face and scalp, the entire body should be painted with the dilute solution, which is rubbed well in and left to dry. About ten minutes is allowed for the skin to dry naturally and the patient then dresses. Application is suitable for use in clinics dealing with children. In difficult cases this routine may be repeated successively for two or three days. These instructions are applicable to adults and children.

Contraindications

Known idiosyncratic response to its application. The solution should not be applied near a naked flame. Because of the close chemical relationship between monosulfiram and disulfiram, it is advisable to abstain from alcohol before and for at least 48 hours after the application of Monosulfiram

Side Effects

Very few side-effects occur with Monosulfiram Solution even in cases of undiluted application. A few cases of erythematous rash considered as idiosyncratic response have been reported.

Pregnancy & Lactation

Pregnancy Category is not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Precautions & Warnings

Therapeutic Class

Parasiticidal preparations

Storage Conditions

Store at room temperature (below 35°C). Monosulfiram Solution should not be stored in a cold place as this causes deposition of crystals. These can be redissolved by immersing the bottle in warm water. The solution is flammable and should not be kept near naked flame. Water is a suitable diluents for Monosulfiram.