Indications

Faropenem tablet is indicated in the treatment of the following infections: Lower respiratory tract infections : acute bronchitis, pneumonia, pulmonary suppuration. Ear, nose, and throat (ENT) infections : otitis externa, tympanitis, sinusitis. ... Read more Faropenem tablet is indicated in the treatment of the following infections: Lower respiratory tract infections : acute bronchitis, pneumonia, pulmonary suppuration. Ear, nose, and throat (ENT) infections : otitis externa, tympanitis, sinusitis. Genito-urinary infections : pyelonephritis, cystitis, prostatitis, seminal gland inflammation. Upper respiratory tract infections : pharyngitis, tonsillitis. Skin and skin structure infections : pustular acne, folliculitis, contagious impetigo, erysipelas, lymphangitis, suppurative nail inflammation, subcutaneous abscess, hidradenitis (sweat gland inflammation), infective sebaceous cyst, chronic pyoderma, secondary infection of external wounds or surgical wounds. Gynecological infections : adnexitis, bartholin gland inflammation.

Composition

Pharmacology

Faropenem is a penem class of antimicrobial and has bactericidal activity against a variety of gm-ve, gm+ve and anaerobic bacteria. Faropenem is bactericidal, with a strong affinity for the high molecular penicillin binding proteins (PBPs) of the cell wall, which is essential for the multiplication of bacilli; it, thus, acts by inhibiting the cell wall synthesis. Faropenem shows broad antibacterial activity against both aerobic and anaerobic Gram-positive and Gram-negative bacteria. Faropenem is highly stable against various beta lactamases and binds preferentially to the PBPs, 2 and 1A, of Escherichia coli (E. coli).

Dosage & Administration

Upper respiratory tract infections : 150 mg t.i.d., can be increased to 200 mg t.i.d. ENT infections : 200 mg t.i.d., can be increased to 300 mg t.i.d. Lower respiratory tract infections : 200 mg t.i.d., can be increased to 300 mg t.i.d. Skin and skin structure infections : 150 mg t.i.d., can be increased to 200 mg t.i.d. Genito-urinary infections : 200 mg t.i.d., can be increased to 300 mg t.i.d. Gynecological infections : 150 mg t.i.d., can be increased to 200 mg t.i.d.

Contraindications

Faropenem is contraindicated in patients with known hypersensitivity to any of the components of this product or to other drugs in the same class, or in patients who have demonstrated anaphylactic reactions to beta-lactams.

Side Effects

Common side effects of this drug are Headache, Nausea, Vomiting, Stomach pain and Diarrhea.

Pregnancy & Lactation

Safety regarding therapy during pregnancy has not been established. In pregnant women or expectant mothers, the medicine should be given only if the benefit of the treatment is greater than the risks involved. Faropenem is excreted in human milk. Therefore, Faropenem should be given to nursing mothers only if the benefits outweigh the risks.

Precautions & Warnings

Faropenem should be administered with caution in the following: Patients with a past history of hypersensitivity to penicillin, cephem or carbapenem drugs. Patients with a family history of atopy. Patients with renal impairment. The dosage should be reduced or the interval between doses should be increased. Geriatric patients. Patients with poor oral intake or poor general state (since there are cases that show symptoms of vitamin K deficiency, proper monitoring should be done).

Therapeutic Class

Storage Conditions

Store Faropenem at room temperature between 20°C to 25°C in its original package. Safely throw away any Faropenem that is out of date or no longer needed. Keep Faropenem and all medicines out of the reach of children. Protect from moisture.