নির্দেশনা

This combination capsule is indicated in: Support for cardiovascular health Contribute to normal absorption and utilization of calcium and phosphorous in the body Contribute to normal blood clotting Contribute to the maintenance of normal bones

Composition

• Vitamin Ds (4000 IU) &
• Vitamin K2 (100 mcg).

ফার্মাকোলজি

Vitamin K2 is necessary for the activation of osteocalcin, a protein that transports and integrates calcium into bone to ensure a healthy skeleton. Incorporating calcium into the bone matrix means that less calcium is available for harmful deposits in soft body tissues. Vitamin D3 (Cholecalciferol) is essential for normal bone growth & development and to maintain bone density. It also helps our body to utilize both Calcium & Phosphorus. The active form of Vitamin D3, Calcitriol, exerts its effect by binding to the Vitamin D receptors (VDRs) which are widely distributed through many body tissues.Vitamin D3 has a half life of about 50 days as it is fat soluble.Vitamin D3 is absorbed in the small intestine and bound to specific a-globulins and transported to the liver where it is metabolised to 25-hydroxy Vitamin D3 (Calcidiol). A second hydroxylation to 1,25-dihydroxy Vitamin D3 (Calcitriol) occurs in the kidney. This metabolite is responsible for the vitamin's ability to increase the absorption of calcium. Non-metabolised Vitamin D3 is stored in tissues such as fat and muscle.Vitamin D3 is eliminated via faeces and urine.

মাত্রা ও সেবনবিধি

Adults and children over 12 years of age: 1-2 capsule daily or as directed by the physician.

প্রতিনির্দেশনা

Contraindicated in patients with known hypersensitivity to any of the ingredients.

পার্শ্ব প্রতিক্রিয়া

Well tolerated in recommended dose.

গর্ভাবস্থায় ও স্তন্যদানকালে

Vitamin K & D3 is safe in pregnancy & lactation when used as recommended doses.

সতর্কতা

থেরাপিউটিক ক্লাস

Herbal and Nutraceuticals

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