নির্দেশনা

Pranlukast is indicated for asthma and allergic rhinitis symptoms.

Composition

ফার্মাকোলজি

Pranlukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor in the human airway. It inhibits the actions of LTD4 at the CysLT1 receptor and prevents airway edema, smooth muscle contraction and enhanced secretion of thick, viscous mucus.

মাত্রা ও সেবনবিধি

Child : 3.5 mg/kg bid. Max dose : 10 mg/kg/day (not exceeding 450 mg daily). Adults : Take 2 tablets (225 mg) at a time, twice a day after breakfast and dinner. The dosage may be adjusted according to your age and symptoms. Strictly follow the instructions. Use in Children & Adolescents : There was a substantial benefit of adding pranlukast to usual therapy in asthmatic children.

প্রতিনির্দেশনা

Pranlukast is contraindicated in acute asthma attacks and hepatic impairment/cirrhosis.

পার্শ্ব প্রতিক্রিয়া

Headache, increased incidence of respiratory tract infection, GI disturbances, induced generalized pain, fever, myalgia and arthralgia.

গর্ভাবস্থায় ও স্তন্যদানকালে

Use of pranlukast is not associated with an increased risk of pregnancy loss, gestational diabetes, preeclampsia, low maternal weight, preterm delivery, low apgar scores and reduced measures of birth length in infants. Slightly decreased birth weight in infants born to pranlukast users could be attributed to maternal asthma severity/control.

সতর্কতা

Should be cautious regarding the patients with renal impairment. Possible elevations in liver enzymes can happen. Withdraw treatment in patients showing signs consistent with Churg-Strauss syndrome.

থেরাপিউটিক ক্লাস

সংরক্ষণ